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Este estudio tuvo como objetivo evaluar la eficacia del protocolo alternativo con láser CO2 fraccionado combinado con radiofrecuencia fraccionada con microagujas (FMR) y plasma rico en plaqueta (PRP), en el tratamiento de estrías presentes en glúteos. Se desarrolló una investigación cuasiexperimental, en el que se realizaron 3 sesiones en 12 pacientes, a los cuales se les aplicó únicamente láser CO2 fraccionado en el glúteo izquierdo y terapia combinada de láser CO2 fraccionado, FMR y PRP en el glúteo derecho. Las pacientes presentaron una severidad de estrías entre leve (75%) y moderada (25%), según la Escala de Severidad de las Estrías (SDSS) modificada y adaptada para glúteos. La media del SDSS antes del tratamiento para el glúteo izquierdo fue de 6,83 y de 6,75 para el glúteo derecho. Posterior al tratamiento únicamente con láser CO2 aplicada en el glúteo izquierdo, se encontró una disminución (p=0,015) del índice del SDSS (5,49; IC95%: 4,72–6,26), mientras que, para el glúteo derecho (tratamiento combinado), se encontró una mayor disminución (p=0,0001) del SDSS (4,09; IC95%: 3,20–4,97). El 100% de los pacientes y 93,3% de los médicos especialistas reportaron una mejora de la apariencia del glúteo que se colocó láser CO2 combinado, según puntuación de la Escala de Mejora Estética Global (GAIS). En conclusión, el tratamiento combinado generó una mejoría clínica de las estrías superior (39%) al ser comparada con el tratamiento que solo se aplicó láser CO2 fraccionado (20%).
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