Abstract
Genitourinary Syndrome of Menopause (GMS) is one of the most frequent reasons for women's consultation in gynecology, presenting with a prevalence of 50 to 80% in postmenopausal women. Therefore, it is necessary to offer patients a safe, effective, and time-adherent treatment. This work proposes to compare the effectiveness and safety of the 10,600nm CO2 laser and 2,940nm Er:YAG. in the treatment of symptoms related to GMS. For this, vaginal health, urinary incontinence, sexual function, biopsy analysis, and cytology were comprehensively evaluated before and after applying three treatment sessions with the CO2 and Er:YAG laser, independently, to two groups. of women in private gynecology practice. Good tolerance of the intervention and high satisfaction rates were obtained for both protocols (CO2 and Er:YAG), in addition to similar success values in increasing (p<0.05) vaginal health and decreasing SUI. , with an improvement in atrophic epithelial tissue. Compared with the Er:YAG laser, the CO2 laser achieved better results in terms of reducing the severity of clinical symptoms, a 39% increase in sexual function, a greater number of young fibroblasts, and neovascularization in the epithelium. None of the described protocols presented adverse effects during and after application in patients with SGM. In conclusion, both laser platforms are a safe, effective, and well-tolerated outpatient alternative for vaginal functional restoration in the treatment of GMS.
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