Abstract
Uterine leiomyomas, also known as fibroids, are the most common tumors in women of reproductive age, often associated with abnormal uterine bleeding and reproductive issues. This study evaluated the efficacy of the 1470 nm Diode Laser for performing hysteroscopic myolysis in the office. A prospective longitudinal case series study was conducted with 10 patients: women over 18 years old, diagnosed with 1 or 2 symptomatic submucosal fibroids (grade 0-2 FIGO) ≤5 cm in size. Patients were informed about the procedure, risks, and benefits, and signed an informed consent document. A 1470 nm Diode Laser with an 800-micron fiber was used, achieving optimal water absorption and the desired vaporization effect. The average procedure duration, from the insertion of the hysteroscope into the uterine cavity to the completion of fibroid core coagulation and vaporization, was 9.6 minutes. Intraoperative blood loss was estimated to be insignificant in all patients. No procedures were aborted or interrupted. The average pain level immediately after the procedure, documented on the visual analog scale, was 1 in 40% of patients, 2 in 30%, 4 in 20%, and 5 in 10%. Six patients had FIGO class 2 submucosal fibroids, three had class 0, and one had class 1. The average fibroid volume before the procedure was 2.75 mm (0.5-6.0 mm), and the average fibroid volume after the procedure was 0.10 mm. Of the four patients evaluated postmyolysis at 8 weeks, only one had a significantly reduced fibroid from 2.5 cc to 0.4 cc; the remaining three showed no ultrasound evidence of uterine fibroids, indicating a favorable response to laser vaporization. No pre- or post-surgical complications were reported.
References
Hernández-Valencia M, Valerio-Castro E, Tercero-Valdez-Zúñiga CL, Barrón-Vallejo J, Luna-Rojas RM. Miomatosis uterina: implicaciones en salud reproductiva. Ginecol. obstet. Méx. 2017; 85(9): 611-633. Disponible en: https://pesquisa.bvsalud.org/portal/resource/pt/biblio-953754
Fabregues, F., Penarrubia, J. Mioma uterino. Manifestaciones clínicas y posibilidades actuales de tratamiento conservador. Med int. 2002;40(5): 190-195. Disponible en: https://www.elsevier.es/es-revista-medicina-integral-63-pdf-13036877
Munro, M. G., Critchley, H. O., & Fraser, I. S. La clasificación FIGO de causas de sangrado uterino anormal en los años reproductivos. Revista del climaterio. 2011 15(85), 9-17. Disponible en: https://silo.tips/download/la-investigacion-y-el-manejo-del-sangrado-uterino
Instituto Mexicano del Seguro Social. Guía de Práctica Clínica para Diagnóstico y Tratamiento de Miomatosis Uterina, México. 2010. Disponible en: https://www.imss.gob.mx/sites/all/statics/guiasclinicas/082GER.pdf
Valentín LN, Bradley LD. Histeroscopia para sangrado uterino anormal y fibromas. Clin Obstet Gynecol. 2017;60(2):231–244. Disponible en: DOI: 10.1097/GRF.0000000000000287
Carranza-Mamane B, Havelock J, Hemmings R. El tratamiento de los fibromas uterinos en mujeres con infertilidad inexplicable. J Obstet Gynaecol Can. 2015;37(3):277–285. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S1701216315303182
Yendru KS, Yelamanchi SD, Vaddiraju GB. Resección histeroscópica de miomas submucosos en mujeres sintomáticas. J Obstet Gynaecol India. 2019;69(2):166–172. Disponible en: DOI: https://doi.org/10.1007/s13224-018-1139-z
Haimovich S, Lopez-Yarto M, Urresta Avila J, et al. Enucleación histeroscópica con láser en consultorio de miomas submucosos sin extracción de masa: un estudio de serie de casos. Biomed Res Int. 2015; 2015:905204. Disponible en: https://www.tesisenred.net/bitstream/handle/10803/392663/shs1de1.pdf?sequence=1&isAllowed=y
Nappi L, Pontis A, Sorrentino F, et al. Metroplastia histeroscópica para el útero tabicado con láser de diodo: un estudio piloto. Eur J Obstet Gynecol Reprod Biol. 2016; 206:32–35.Disponible en:https://pubmed.ncbi.nlm.nih.gov/27632410/
Kremer C, Duffy S, Moroney M. Patient satisfaction with outpatient hysteroscopy versus day case hysteroscopy: randomized controlled trial. NMJ 2000; 320:279. Disponible en: https://pubmed.ncbi.nlm.nih.gov/10650023/
Munro MG, Critchley HOD, Fraser IS. Los dos sistemas FIGO para síntomas de sangrado uterino normal y anormal y clasificación de causas de sangrado uterino anormal en los años reproductivos: revisiones de 2018. Int J Gynaecol Obstet. 2018; 143(3):393–408. Disponible en: http://www.fasgo.org.ar/images/Consenso_Sangrado_uterino_anomalo.pdf
SG vitale, O. Moore, Haimovich S, et al. Ablación histeroscópica con láser en fibromas uterinos sintomáticos: conocimiento de un estudio prospectivo. Climateric. 2023. Disponible en: : http://doi.org/images/10.1080 13697137.2023.2205581

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