Keywords
Nd:YAG Laser
photobiomodulation
chemical peel
hyperpigmentation
How to Cite
Abstract
Objective: To evaluate the clinical effectiveness and safety of a triphasic treatment protocol based on Q-Switched 1064 nm Nd:YAG laser, photobiomodulation therapy, and chemical peels in patients with melasma. Methods: A prospective case series was conducted in 10 female patients diagnosed with melasma. Participants underwent a combined treatment protocol over a six-month period, including Q-Switched 1064 nm Nd:YAG laser, photobiomodulation therapy, and chemical peels. Clinical assessment, standardized photographic documentation, melasma classification, therapeutic response, adverse effects, and patient satisfaction were evaluated throughout the follow-up period.Results: Mixed melasma was the most frequent subtype before treatment (50.0%), followed by epidermal (30.0%) and dermal melasma (20.0%). At the end of treatment, lesion extension decreased in 80.0% of patients, while 50.0% showed improvement in skin brightness and texture. No cases of epidermal melasma were observed after treatment. Adverse effects were mild and transient, with burning sensation (60.0%) and erythema (30.0%) being the most common. Overall, 80.0% of patients reported complete satisfaction with the treatment outcomes.Conclusions: The triphasic protocol combining Q-Switched 1064 nm Nd:YAG laser, photobiomodulation therapy, and chemical peels proved to be a safe and effective therapeutic option for melasma management, promoting reduction of facial hyperpigmentation, improvement in skin quality, and high patient satisfaction.
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