Palabras clave
quemaduras
láser CO₂ fraccionado
exosomas
POSAS
VSS
Cómo citar
Resumen
Las cicatrices postquemaduras representan un desafío clínico por su impacto estético, funcional y emocional en los pacientes. Esto ha impulsado el desarrollo de terapias innovadoras que promuevan la regeneración cutánea y mejoren la calidad de vida. Este estudio tuvo como objetivo evaluar la eficacia del láser fraccionado de CO₂, aplicado como monoterapia y en combinación con exosomas sintéticos (terapia dual), en el tratamiento de cicatrices por quemaduras. Se analizaron 12 cicatrices tratadas en cuatro sesiones, distribuidas en dos protocolos: láser CO₂ fraccionado solo y láser CO₂ fraccionado con exosomas. Desde la segunda sesión, ambos tratamientos mostraron mejoras significativas (p < 0,05) en flexibilidad, grosor, relieve, elasticidad y reducción de superficie, según las escalas de Cicatrización de Vancouver (VSS) y de Evaluación de Cicatrices por Observador y Paciente (POSAS). La terapia dual presentó resultados superiores (p < 0,05), con mejoras del 33,5% en VSS, 46,1% en POSAS médico y 40,8% en POSAS paciente, superando a la monoterapia. En conclusión, el láser fraccionado de CO₂, especialmente combinado con exosomas sintéticos, constituye una alternativa ambulatoria, segura y eficaz para el tratamiento de cicatrices por quemaduras, favoreciendo la restauración funcional y estética de la piel.
Citas
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