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Abstract
In order to determine the effect of the 980 nm Diode Laser in the treatment of vulvar, vestibular and perianal condylomatosis, a case study was carried out in three patients who attended the Gynecological consultation at the “Leopoldo Aguerrevere” Maternity Clinic Center between February and August 2020. The patients shared characteristics such as age, skin phototype, type, size, number and location of lesions, response to treatment, and side effects. Regarding the skin phototypes seen, phototype II, IV and V were found. Before treatment, 66.7% of all the lesions in the three patients had bunches of grapes form, one of them with 25 lesions on the right lip majora. 15 in the left labia majora and 6 in the vestibular region; in the other two patients, 15 were located in the right labia minora, 25 in the left labia minora, and 10 in the vestibular region, and 18 in the right labia minora, 8 in the left labia minora, and 8 in the vestibular region. Two of the patients received two sessions and one patient three sessions. The percentage of total remission of the lesions after the second session ranged between 38.0% and 100% and in the patient in whom 3 sessions were fulfilled, the remission of injuries was absolute. Given the results in the present study, it can be concluded that condylomatous lesions can be treated with a 980 nm Diode Laser, since it considerably reduces both the number and appearance of lesions and it is effective while having very few side effects.
References
Camacho F, García J, Pérez A. Modelación Cutánea (resurfacing) Conceptos y fundamentos en Cisneros V, Camacho M, editores. Láser en Dermatología y Dermocosmética. Madrid (España): Editorial Grupo Aula Médica.2007. p. 205-216.
Sarmiento V y Torres V. Rejuvenecimiento facial. Abordaje terapéutico. [Internet]. 2006. México. [citado 8 de abril de 2020]. Recuperado a partir de: https://www.yumpu.com/es/document/view/42597276/185-rejuvenecimiento-facial-abordaje-terapacutico-antonio-
Martínez-Carpio PA., Trelles MA.. El láser y la fotónica en la Cirugía Plástica española e iberoamericana: Antecedentes históricos, aplicaciones actuales y proyectos de desarrollo inmediato. Cir. plást. iberolatinoam. [Internet]. 2010 [citado 8 abril 2020]; 36(1):59-78. Disponible en: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0376-78922010000100010&lng=es
Kohl E, Babilas P, Landthaler M. Skin Rejuvenation with Intense Pulsed Light. Acta Dermatovenerol Croat. Lasers in treatment of aging skin 2010; 18(3):181-184.
Gold M, Bradshaw V, Boring M, Bridges T, Biron J. Split-face comparison of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone for photodamage. Dermathologic Surgery. 2006; 32 (6): 795-803.
Garín C, Arruebo M (dir). Photodynamic therapy in the Treatment of skin asociated infections. [Master]. [España]. Universidad Zaragoza. 2019.
Kostovié K, Pastar Z, Ceovíe R, Mokos Z, Bozine D, Saimiri A. Photodynamic Therapy in Dermatology: Current Treatments and Implications. Coll. Antropol. 36 (2012) 4: 1477–1481.
Peterson J, Massaki A, Goldman M. Photodynamic Therapy en Avram M, Mathew A, Friedman P, autores. Laser and Light Source Treatments for the Skin. Editorial JP Medical Ltd. 2014. p 69- 142.
Rossi R, Lotti T, Bruscino N. Photodynamic Therapy/Assisted Photorejuvenation. Journal of Cosmetics, Dermatological Sciences and Applications. [Internet]. 2011; [citado 8 abril 2020]. 1(2): 313 -6. Disponible en: http://www.scirp.org/journal/PaperInformation.aspx?PaperID=5313
R. R. Ruiz, T. Sanz-Sanchez and S. Cordoba, “Photodynamic Photorejuvenation,” Dermatologic Surgery. [Internet]. 2002 [citado 8 abril 2020] ; 28 (8): 742-744. Disponible en: https://doi.org/10.1046/j.1524-4725.2002.02018.x
Ruiz R, López L, Candelas D, Pedraz J. Photorejuvenation using topical 5-methyl aminolevulinate and red light. Journal of Drugs in Dermatology: JDD. 2008; 7(7):633-637.
Marmur E, Phelps R, Goldberg D. Ultrastructural changes seen after ALA-IPL photorejuvenation: a pilot study. J Cosmet Laser Ther. [Internet]. 2005 [Citado 8 abril 2020].; 7(1):21-4. Disponible en: https://doi.org/10.1080/147641700510037725
Avram DK, Goldman MP. Effectiveness and safety of ALA-IPL in treating actinic keratoses and photodamage. J Drugs Dermatol. 2004; 3(1): 36-9.
Dover J, Bhatia A, Stewart B, Arndt K. Topical 5-Aminolevulinic Acid Combined with Intense Pulsed Light in the Treatment of Photoaging. Arch dermatol. [Internet]. 2005. [Citado 8 abril 2020]; 141(10): 1247- 52. Disponible en: https://jamanetwork.com/journals/jamadermatology/fullarticle/399885
Gold M, Bradshaw V, Boring M, Bridges T, Biron J. Split‐Face Comparison of Photodynamic Therapy with 5‐Aminolevulinic Acid and Intense Pulsed Light versus Intense Pulsed Light Alone for Photodamage Dermatologic Surgery. 2006; 32 (6); 795-803.
Freeman M, Vinciullo C, Francis D, Spelman L, Nguyen R, y col. A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix®) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study Journal of Dermatological Treatment 2009: 14 (2): 99-106.
Almeida M, Barcauí C, Cariello A, Ramos F, Manela M. Intense Pulsed Light alone versus Intense Pulsed Light and aminolevulinic acid in the treatment of photodamaged skin: importance of long-term follow-up. Surgical & Cosmetic Dermatology 2009; 1 (3):125-129.
Yang G, Xiang L, Gold M. 5-Aminolevulinic Acid-based Photodynamic Intense Pulsed Light Therapy Shows Better Effects in the Treatment of Skin Photoaging in Asian Skin A Prospective, Single-blinded, Controlled Trial. The Journal of Clinical and Aesthetic Dermatology. 2010; 3 (3): 40-43.
Xi Z, Shuxian Y, Zhong L, Hui G, Yan W, y col. Topical 5-Aminolevulinic Acid with Intense Pulsed Light versus Intense Pulsed Light for Photodamage in Chinese Patients. Dermatologic Surgery.2011; 37(1):31–40.
Gold M, Biron J. Safety and Cosmetic Effects of Photodynamic Therapy using Hexyl Aminolevulinate and Intense Pulsed Light A Pilot Study Conducted in Subjects with Mild-to-moderate Facial Photodamage. The Journal of Clinical and Aesthetic Dermatology. 2013; 6 (10): 27-31.
Kyung B, Lee N, Park S, Eom M, Choi E. Efficacy of photodynamic therapy with laser pretreatment for actinic keratosis and photorejuvenation as evaluated by fluorescent imaging. Photodermatology Photoinmunology & Photomedicine.2015; 31(1): 36-43.
Shin HT, Kim JH, Shim J, Lee JH, Lee DY, y col. Photodynamic therapy using a new formulation of 5-aminolevulinic acid for wrinkles in Asian skin: A randomized controlled split face study. J Dermatolog Treat.. [Internet]. 2015 [Citado 8 abril 2020]; 26(3):246-51. Disponible en: https://pubmed.ncbi.nlm.nih.gov/24913131/
Wangsuwan S, Meephansan J. Photodynamic therapy with riboflavin-tryptophan gel in facial skin rejuvenation: a pilot study. Thai Journal of Pharmaceutical Sciences.. [Internet]. 2018. [Citado 8 abril 2020]; 42: 206- 210. Disponible en:
Hendel K, Mogensen M, Wenande E, Dierickx C, Haedersdal M, y col. Fractional 1,927nm Thulium Laser Plus Photodynamic Therapy Compared and Combined for Photodamaged Décolleté Skin: A Side‐by‐Side Randomized Controlled Trial. Lasers in Surgery and Medicine. [Internet]. 2020. [Citado 8 abril 2020]; 52:44–52 Disponible en: https://onlinelibrary.wiley.com/doi/full/10.1002/lsm.23194
Patel G, Armstrong A, Eisen D. Efficacy of photodynamic therapy vs other interventions in randomized clinical trials for the treatment of actinic keratoses: a systematic review and meta-analysis. JAMA Dermatol. 2014; 150(12):1281-8.
Sanclemente G, Ruiz V, Miranda J, Ferrína A, Ramirez P, Hernandez G. Terapia fotodinámica en el fotodaño facial: revisión sistemática. Actas Dermo-Sifiliográficas. [Internet]. 2018. [citado 8 abril 2020].; 109 (3): 218-229. Disponible en: https://doi.org/10.1016/j.adengl.2017.05.026
Ji J, Zhang L, Ding H, Wang H, Huang Z, y col. Comparison of 5-aminolevulinic acid photodynamic therapy and red light for treatment of Photoaging. Photodiagnosis and Photodynamic Therapy. 2014: 11 (2): 118-121.
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